Molecular Details
DICL_CP_0307532
- 1H-indol-5-ol
Basic Molecular Information
Basic Information
DICL ID
DICL_CP_0307532
PubChem CID
Molecular Formula
C8H7NO Molecular Weight
133.15 g/mol
Synonyms/Alias
[5-Hydroxyindole; 1H-Indol-5-ol; 1953-54-4; INDOL-5-OL; 5-Hydroxy-1H-indole; Hydroxy-5 indole; MFCD00005677; C8H7NO; NSC-87503; 320UN7XZYN; CHEBI:89649; 5-Indolol; 5-hydroxy-indole; Hydroxy-5 indole [...
InChI Key
LMIQERWZRIFWNZ-UHFFFAOYSA-N
InChI
InChI=1S/C8H7NO/c10-7-1-2-8-6(5-7)3-4-9-8/h1-5,9-10H
IUPAC Name
1H-indol-5-ol
CAS Number
2250059-52-8
Structure Information
Chemical Structure Visualization
SMILES Notation
2D Molecular Drawing
Carbon (C)
Hydrogen (H)
Oxygen (O)
Nitrogen (N)
Sulfur (S)
SDF
17 18 0 0 0 0 0 0 0 0999 V2000
1.6758 0.9907 0.2620 C 0 0 0 0 0 0 0 0 0 0 0 0
0.3690 1.5117 0.2940 C 0 0 0 0 0 0 0 0 0 0 0 0
-0.6886 0.629...
Experimental Data
Activity Data
Target Ion Channel
Neuronal acetylcholine receptor subunit alpha-7
Uniprot Accession Number
Function
Agonist
Species
Homo sapiens (Human)
IC50
N/A (Not available)
EC50
EC50: 2500000 nM
Ki
N/A (Not available)
Kd
N/A (Not available)
Inhibition
N/A (Not available)
Experimental Conditions
pH
pH 7.3
Holding Potential
−60 mV mV
Temperature
Not mention
Test Method
Patch-clamping
Test Species
Xenopus laevis oocyte
Binding Information
Binding Site
Not specified
Binding Site Residue
Not specified
Disease Information
Related Disease
Not specified
References
Computed Properties
Heavy Atom Count
10
Rotatable Bonds
0
logP
1.8735
Complexity
39.9635
TPSA (Ų)
36.02
H-Bond Donors
2
H-Bond Acceptors
1
Ring Count
2